Microfluidic encapsulation method to produce stable liposomes containing iohexol
نویسندگان
چکیده
منابع مشابه
A facile microfluidic method for production of liposomes.
BACKGROUND Ethanol injection is widely used in liposome preparation. However, the parameters determining particle size distribution of the liposomal preparation has not been fully defined. MATERIALS AND METHODS A syringe pump-driven microfluidic injection device was used to produce liposomes under different conditions. RESULTS Particle size of the liposomes was decreased with decrease in ne...
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The purpose of this study was to optimize a method for the encapsulation of P5 peptide, a new designed peptide containing MHC class I epitopes from rat HER2/neu protein, into liposomes as an approach for breast cancer vaccine formulation. The efficiency of liposomal encapsulation of peptides is generally low and development of an optimized method to increase encapsulation efficiency is a big ch...
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BACKGROUND Liposomes have been successfully used as delivery vehicles for anticancer drugs. Both sonication and microfluidic technologies have been used to produce liposomes. The combination of the two methods was evaluated in this study. MATERIALS AND METHODS The microfluidic devices, mainly comprising micro-dispensers and a sonicator, were used to produce liposomal nanoparticles. Sonication...
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ژورنال
عنوان ژورنال: Journal of Drug Delivery Science and Technology
سال: 2019
ISSN: 1773-2247
DOI: 10.1016/j.jddst.2019.101340